EUPHIX (www.euphix.org)

EUPHIX, European Public Health Information, Knowledge & Data Management System
Influenza
European Union definition of influenza

Clinical criteria

Any person with at least one of the following clinical forms:

Influenza-like illness (ILI)

Sudden onset of symptoms

AND

At least one of the following four systemic symptoms:

AND

At least one of the following three respiratory symptoms:

  • Cough
  • Sore throat
  • Shortness of breath

Acute respiratory infection (ARI)

Sudden onset of symptoms

AND

At least one of the following four respiratory symptoms:

  • Cough
  • Sore throat
  • Shortness of breath
  • Coryza

AND

A clinician's judgement that the illness is due to an infection

Laboratory criteria

At least one the following four:

  • Isolation of influenza virus from a clinical specimen
  • Detection of influenza virus nucleic acid in a clinical specimen
  • Identification of influenza virus antigen by DFA test in a clinical specimen
  • Influenza specific antibody response

Sub typing of the influenza isolate should be performed, if possible

Epidemiological criteria

An epidemiological link by human to human transmission

Case classification
  • Possible case: any person meeting the clinical criteria (ILI or ARI)
  • Probable case: any person meeting the clinical criteria (ILI or ARI) and with an epidemiological link
  • Confirmed case: any person meeting the clinical (ILI or ARI) and the laboratory criteria