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The Framingham Heart Study is a landmark study that identified many risk factors and characteristics od cardiovascular diseases for the first time. The initial study started in 1948 in the town of Framingham, Massachusetts, USA. Initially, 5,209 men and women aged 30 to 62 years free of cardiovascular disease participated in the study. Study participants were extensively examined and interviewed at baseline and regularly followed up with regard to the development of cardiovascular diseases. Meanwhile the Framingham Study includes also a second generation study cohort, the so-called Framingham Offspring Study that started in 1971, and the Generation III cohort which is currently being recruited and examined. Currently, more than 1300 scientific reports from the Framingham Study have been published. For more information see the US National Heart Lung and Blood Institute website.
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